3/18/2024 0 Comments Pbp3 check compiled size![]() The MTB XDR1219 interactome consists of 11,383 non-redundant PPIs among 1499 proteins covering 38% of the entire MTB XDR1219 proteome. The pipeline adopted the combination of an extensive integrated network analysis that led to identify 22 key proteins involved in drug resistance, resistant metabolic pathways, virulence, pathogenesis and persistency of the infection. In this work, a bioinformatics approach was employed to reveal potential drug targets. The current study focused on the construction of PPI network for the human pathogen Mycobacterium tuberculosis (MTB)-resistant strain XDR1219 using computational methods. ![]() The interactome of most organisms is largely unidentified except some model organisms. The reconstruction and analysis of the protein–protein interaction (PPI) network is a powerful approach to understand the complex biological and molecular functions in normal and disease states of the cell. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |